nfl Preview< BACK

San Francisco 49ers vs. Pittsburgh Steelers

Acrisure Stadium has a Week 1 contest on tap for Sunday as the San Francisco 49ers and the Pittsburgh Steelers play their season openers.

Oddsmakers opened the 49ers as -2.5-point favorites versus the Steelers, while the game's total opened at 43.5.

In their last action, Pittsburgh was a 28-14 winner at home against the Browns. They covered the -2.5-point spread as favorites, while the combined score (42) was profitable news for OVER bettors.

In their last action, San Francisco was a 31-7 loser on the road against the Eagles. They failed to cover the +2.5-point spread as underdogs, while the combined score (38) was profitable news for UNDER bettors.

Next up:
San Francisco at Los Angeles Sunday, September 17
Pittsburgh home to Cleveland Monday, September 18